Q: What is repolarizes? What is action potentials and when does it occur so that all cells are firing it? Is the resting membrane potential of the cell, the ICF? In question 3, do I have to use the information that Cl concentration in the ECF is 150mM and the Cl concentration in the ICF is 15mM, so that I can solve this problem? Lastly, is it alright that you explain to me about the open and closing of Cl channels? I really don't understand it. The only thing I get from it is that it needs to be trigger into being the open state. I'm assuming that the Cl channel only allows Cl to enter into the cell.
A: My answers to your questions are below:
This animation explains it better than I can through email (see link below). I also expect that Dr. Rechs will get to action potentials next week, if he hasn't already. There is also an explanation in your text book.
and when does it occur so that all cells are firing it?
To fire an action potential, the cells need a stimulus.
Is the resting membrane potential of the cell, the ICF?
I'm sorry, I don't quite understand what you are asking here. The ICF simple means "intracellular fluid." Resting membrane potential is explained in detail on page 17 of your lab manual.
In question 3, do I have to use the information that Cl concentration in the ECF is 150mM and the Cl concentration in the ICF is 15mM, so that I can solve this problem?
Yes, you can use those numbers if you want. The important thing is that you know that there is a higher Cl- concentration in the ECF than the ICF.
Lastly, is it alright that you explain to me about the open and closing of Cl channels? The only thing I get from it is that it needs to be trigger into being the open state.
The only thing you need to know is that the Cl channels are normally closed and GABA opens these Cl channels. GABA is the trigger.
I'm assuming that the Cl channel only allows Cl to enter into the cell.
Yes, that's right.
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